Adaptation Biology and Medicine: Volume 6:Cell Adaptations and Challenges
Authors: Paulus Wang, Chia-Hua Kuo, Nobuakira Takeda, Pawan K. Singal
978-81-7319-935-6 Publication Year: 2011
Pages: 504 Binding: Hard Back
About the book
In broad terms, the present day existence of all forms of life on earth is the result of adaptation by organisms over time to the given environment/circumstance. More recently, it has also been seen that a gradual adaptation to repeat exposures to different stresses such as hypoxia, heat, cold, infections, exercise, etc. increases the resistance of the organisms not only to each of these stresses, but also to other potentially harmful conditions. An understanding of the science behind the process of such an adaptation is the key to future therapies. Several chapters in this book cover new developments in our understanding of the biology of adaptation at the molecular, cellular, organ and whole body level. Some of the chapters also consider translational aspects of such a knowledge. This book will be of great value to experimental biologists as well as clinicians who deal with a wide variety of disease conditions.
Preface / Acknowledgements / Contributing Authors / Adaptive in Cardiovascular Protections: Injectable Scaffolds for Cardiac Regeneration / Telocytes and Heart Renewing / Stem Cells and Cardioprotection / Synergistic Effect of Magnesium and Diltiazem on Reversal of Myocardial Cell Membrane Stress and Dyskinesia / Adaptive Mechanisms in the Diabetic Myocardium: An Alternative form of Endogenous Cardioprotection and its Loss / Quantitative Alterations in Mitochondria: Adaptation Contra Violation / Role of Sildenafil (ViagraTM) in Cardioprotection and Treatment of Heart Failure / Diabetes/Hyperglycemia differentially Regulate Gi? and Gq? Protein Expression and Associated Signalling in Vascular Smooth Muscle Cells / Redox Regulation of Autophagy in the Ischemic Myocardium / Implication of CaMKII in H2O2-induced Signaling Pathways and in Cardiovascular Pathophysiology / 10 Gy Total Body Irradiation Increases Risk of Coronary Sclerosis, Degeneration of Heart Structure and Function in a Rat Model / Adaptive Programming in Systematic Functions: Hypoxia Inducible Factor (HIF-1a), HSPS, Antioxidant Enzymes and Membrane Resistance to ROS in Endurance Exercise Performance after Adaptive Hypoxic Preconditioning / Human Adaptation to Intermittent Hypoxia: Effects on Hematopoietic Stem Cells and Immune Function / Non-Invasive Measurement of Skeletal Muscle Microvascular Blood Flow using Photoplethysmography: Experimental Studies on the Human Leg / Adaptative Response of Lower Extremity Veins to the Iliac Valve Regurgitation Disease / Alveolar Macrophages Phenotype: Adaptive Programming and Disorders in Pulmonary Diseases / Lung Surfactant System: Effects of Gravity and Restraint Stress / The Thioredoxin and Thioredoxin Reductase System: Overexpression in Thyroid Cancer / The Signal Function of Succinate and Free Radicals in Mechanisms of Preconditioning and Long-term Adaptation to Hypoxia / Role of mRNA Expression of Hypoxia Inducible Factor Subunits in Adaptation to Hypoxia / Role of Nitric Oxide (No) Stores in Adaptive Defense Against No Overproduction / Biological Approach Using Hyperbaric Oxygen Therapy to Improve Ligament Healing in a Rabbit Model / Environmental and Lifestyle Adaptations: Mild Traumatic Brain Injury in Athletes / Protective Effect of Endurance Exercise Training on Brain Antioxidant System in Old Age Rats Treated with Alcohol: A Comparison with Young Age Rats / Assessment of Physiological Biomarkers Involved with Acute Fatigue/Physical Exhaustion / New Anti–Inflammatory Molecule (AISA 5203-L) Promotes Adaptive Strategies in Cell Aging / Adaptation to Low-Dose Ionizing Radiation: Usefulness Human Health / The Dehydroepiandrosterone Sulfate and Adaptation Against Environmental Challenges / The Role of Cytoprotective HO-1 and its Induction by Plant Adaptogens and Phytochemicals in the Development of an Enhanced Cellular Adaptive Resistance / Propylthiouracil and Steroidogenesis / High-Altitude Diseases: The Implications of Genes, Genetics and Drugs / Effect of Ginsenoside Rb1 on Glucose Uptake and Expression of Glucose Transporters in Animal Cells / Household Food Insecurity in Canadian Adolescents: Adaptation of a Lifestyle and Body Mass Index Consequences / Beyond Fatness and Fitness in Singaporean Youths / Index.