ISBN:
978-81-7319-582-2 Publication Year: 2005
Pages: 329 Binding: Hard Back
About the book
This book offers the most up-to-date information on important topics of neurobiology covering from brain development to diseases. The text is designed to provide the subject material in five sections containing 24 chapters. Section A introduces the structure and development of the brain, showing how they are specialized for the functions they serve. Section B is concerned with hormones and neurotransmitters. The next section addresses the various changes related to aging. The last two sections deal with different types of brain diseases including neurodegenerative diseases. All chapters are written by experts in the field. This book is an account of the remarkable progress made so far in different areas of neurobiology. It will be a valuable source of recent information and reference for students, teachers, clinicians and scientists engaged in teaching and research in Neurobiology.
Key Features
Table
of content
Preface / Section A: Brain structure and development: Neuronal plasticity in developing and adult nervous stem/ Neuronal plasticity in the adult brain:role of polysialylated neural cell adhesion molecule as a promoter of cell-cell interaction/ Development and maturation of astroglial cells/ Section B: Hormones and Neurotransmitters: Role of norepinephrine in thermoregulation during rapid eye movement sleep and its deprivation/ Estrogen effects on the brain: implications for aging and Alzheimer’s disease/ Neurotransmitter receptor gene expression: insulin secretion and cell proliferation/ Serotonin receptor mediated signal transduction in brain: antidepressant drug action/ Section C: Brain Aging: Putative biomarkers of neuronal aging: lipofuschin and lipid peroxidation, effects of drugs/ Oxidative stress in brain aging/ Synergistic effects of physical exercise and antioxidants on aging mammalian brain/ Electrophysiological aging of the brain and pharmacology of aging / Section D: Brain Diseases: The endothelium and cerebrovascular disease/ Mutation in Cu/Zn super oxide dismutase and familial amyotrophic lateral sclerosis/ Molecular mechanism of cerebral ischemia/ Understanding cerebral malaria: perspectives and new insights from signal transduction and cell signaling studies/ Central response to peripheral nerve injury: role of non-neuronal cells/ Fragile X Syndrome/ Genetic variability leading to narcotic abuse: potential implication of single nucleotide polymorphisms/ Section E: Neurodegenerative Diseases: Neurodegenerative diseases involving trinucleotide repeat expansion/ Molecular genetics and biology of polyglutamine diseases/ Neurodegenerative disease: post-traumatic epilepsy/ Huntington disease, an excitotoxic neurodegenerative disorder engineered genetically/ Protective role of sodium pyruvate in hydrogen peroxide induced apoptosis using human neuroblastoma cell line as a model/ Therapeutic strategies for neurodegenerative disorders: leads from herbal extracts