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Adaptation Biology and Medicine: Volume 7: New Challenges
Editor(s): Laurentiu M. Popescu, A. R. Hargens, Pawan K. Singal

ISBN:    978-81-8487-214-9 
E-ISBN:   E 978-81-8487-470-9
Publication Year:   2014
Pages:   522
Binding:   Hard Back
Dimension:   185mm x 240mm
Weight:   1200

About the book

It has become amply clear that all live forms on Earth are the products of the constituent genes expressed under the influence of continuously changing natural environment. By the same token, gene expression is known to be modified by our (or by the modern) environment inclusive of factors such as gravity, altitude, temperature, atmospheric pressure and air quality, physical conditioning as well as nutrition and/or lifestyle. Life would not survive without recruiting endogenous adaptive mechanisms responsive to challenging environmnetal factors, Biology of adaptation as well as application of this knowledge has been discussed in both health and disease conditions such as cardiac ischemia and cardiomyopathies, stroke, dementia, Alzheimer’s, cancer, metal toxicity, etc. The book will be of great interest to experimental biologists and health professionals dealing with benefits and failures of physiological and pathophysiological adaptations. It will also serve as an important source of information for young scientists, postdocs and students.

Table of Contents

Preface / Acknowledgements / Contributing Authors / Adaptations in Disease States: Adaptive Protection Against NO Overproduction and Toxicity in Experimental Alzheimer’s Disease / Maladaptive Myocardial Responses to Hypertension are Attenuated by Omega-3 Fatty Acids and Red Palm Oil Intake / Immunohistochemical Evaluation of the Adaptation of Growth Hormone Receptors in Benign Prostatic Hyperplasia and Prostate Carcinoma / Surfactant Protein D: Endogenous Adaptation Factor for Alveolar Macrophages in Microenvironment Changes / Self-Renewing Heart in the Era of Stem Cells: Who have saved the Heart of Prometheus? / Development and Adaptation in Diabetic Cardiomyopathy / Phosphodiesterase-5 Inhibition With Tadalafil Attenuates Detrimental Proteomic Changes in Type 2 Diabetic Myocardium / Biological Activities of Bacterial Levan and Three Fungal ß-glucans, Botryosphaeran and Lasiodiplodan, Under High Glucose Condition in the Pancreatic ß-cell Line INS-IE / Adaptation to Biological Rhythms and its Basis / Molecular Adaptations of Cancer Cells / Hydrogen Sulfide and Substance P in Acute Pancreatitis / Adaptations in Hypoxia/Ischemia: Novel Strategy for Adaptation to Hypoxia-Hyperoxia Improves Tolerance to Oxidative Stress and Hypoxia / Response of Mitochondrial Thiol-redox Systems to an Oxidant Challenge Caused by Acute Hypoxia: Protective Effect of Adaptation to Hypoxia/Hyperoxia / Astrocytes Are Key Players in Mediating Recovery Following Ischemic Stroke / Imaging the Penumbra: The Pathophysiologic Basis for Therapy of Ischemic Stroke / The Causal Contribution of Selective Blood-Brain Barrier to Glucose Transport in Brain Edema and Function Deterioration After Ischemia and Brain Injury / Mitochondrial ATP-Sensitive Potassium Channels Contribute to Cardiac Remodeling After Myocardial Infarction in Rats / Modeling Catecholaminergic Polymorphic Ventricular Tachycardia and Long-QT Syndrome using Induced Pluripotent Stem Cell-derived Cardiomyocytes / Cellular Mechanisms of Myocardial Ischemia / The Role of Oxidative Stress in the Induction of Transcription Factors at Different Stages of Adaptation to Hypoxia / Role of HIF-1a in Signaling Mechanisms of Urgent and Long-Term Adaptation in Different Regimens of Hypoxic Training / Impact of Altitude Training on Glucose Metabolism / Environment and Lifestyle Adaptations: Cardiac Adaptation in Athletes: Multimodality Imaging Assessment / Surface Electromyography: Technical Developments and Clinical Applications in Sports Medicine / Longitudinal Development of Physical Fitness Among Singaporean Youths: Insights and Lessons from Data Mining / Impact of Daily Physical Activity on the Health-Related Quality of Life and Academic Performance of Primary School Pupils in Singapore / Effects of Lower Body Positive Pressure on Cardiovascular Functions in Young Human Adults / Lifestyle-Related Risk Factors Alter Myocardial Response to Ischemia Via Interference with Cellular Adaptive Mechanisms / Development and Evaluation of Mechanical Counter Pressure Glove for Extravehicular Activity in Space / The Philosophy of Dementias / Challenges in the Neuropathological Diagnosis of Dementias / A Surgeons' Strategy to Create an In Vivo Bioreactor for Generation of Axially Vascularized Tissues and Organoids / Precursors of Interstitial Cells of Cajal in the Human Digestive Tract / Aging: Oxidative Stress and Senescent Cellular Phenotypes / Plant Adaptogens Stimulate Recovery and Survival After Exposure to Copper or Cadmium in Larvae of the Pond Snail Lymnaea Stagnalis / Index.


Biologists, Cardiologists, Neurologists, Pharmacologists, Physiologists, Physicians


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